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The progressive neuro-degeneration seen in a person experiencing Parkinson's Disease is due to three factors:

1. irreversible progressive neuro-degeneration due to brain cell death, caused by too many neuro-toxic factors and inadequate neuro-trophic factors

2. reversible facilitated progressive neuro-degeneration (brain cell death exacerbated by newly introduced factors) ie caused by the depletion of the protective glutathione stores by increased levels of L-dopa and dopamine, allowing neuro-toxin accumulation which kills brain cells, or by vitamin B6 depletion caused by Carbidopa or Benserazide

3. reversible pseudo neuro-degeneration (exacerbation of Parkinson's Disease signs and symptoms by introduced factors, and these signs and symptoms are removed when the introduced factors are removed or appropriately balanced) ie adding L-Dopa leads to depletion of multiple other neurotransmitters and their amino acid precursors, leading to additional symptoms that look like those of Parkinson's Disease, but are reversed when the various depletions are addressed.

Dr Marty Hinz at ParkinsonsClinics.com has refined a protocol over twenty + years that safely rebalances the Relative Nutritional Deficiencies caused by treating Parkinson's Disease with the amino acid L-Dopa and the vitamin B6 depleters Carbidopa or Benserazide. Click here for an overview of the science.

Parkinson's Disease, and the drugs used to treat it can lead to 29 relative nutritional deficiencies that can both mimic and exacerbate the disease symptoms they are being used to treat.

In brief:

dopamine concentrations determine the severity of the symptoms in Parkinson's Disease. The body makes dopamine from the naturally occurring dietary nutrient L-Dopa. In a normal person, normal dietary nutrient intake allows enough dopamine to be made by the healthy nerves. For the Parkinson's Disease patient, who has an increased need for dopamine (damage to the dopamine producing nerves and possibly the dopamine stimulated nerves), enough can not be made from dietary intake (due to negative feedback by the dopamine produced) and a relative nutritional deficiency of the nutrients used to make dopamine, exists while on an optimal diet.

The most effective management of the primary relative nutritional deficiency associated with Parkinson's Disease (inadequate L-Dopa) is to orally supplement with the amino acid nutrient, L-Dopa.

However, the high levels of L-Dopa required to make enough dopamine to control the symptoms of Parkinson's Disease, leads to nausea. This is treated by adding Carbidopa or Benserazide. However they lead to vitamin B6 depletion, which causes other symptoms and potentially an increased death rate (vitamin B6 is necessary for over 300 enzymes to function throughout the body). The increased L-Dopa also leads to potentially 29 other relative nutritional deficiencies, that can cause dysfunctions that exacerbates and/or mimics the symptoms of Parkinson's Disease.

The standard medical approach of treating Parkinson's Disease with only L-Dopa and Carbidopa or Benserazide can lead to nutritional collapse which can cause Parkinson's Disease symptoms to worsen, accelerate the permanent brain damage, and / or cause side effects that appear to be part of the irreversible progression of Parkinson's Disease, but are not.

Dr Hart is one of the first and very few doctors in Australia / New Zealand to have trained with Dr Hinz. Dr Hart uses the amino acid rebalancing protocol pioneered by Dr Hinz to safely address amino acid and neurotransmitter imbalances caused by the underlying Parkinson's Disease process. This is done through the use of L-Dopa to increase dopamine levels at damaged dopaminergic nerve cells, and by the use of 5HTP and vitamin B6 to control the nausea induced by the unbalanced use of L-Dopa. By removing the Carbidopa (or Benserazide), and replacing the vitamin B6 they depleted, the involuntary movements (dyskinesias) can be ceased and the increased risk of death reversed, see the video.