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RE-UPTAKE INHIBITORS

An introduction to the structure and function of the Nervous System can be found here.

 

 

Re-Uptake Inhibitor medications can be fairly specific to particular neurotransmitters ie

    selective serotonin re-uptake inhibitors (SSRI) - Celexa (citalopram), Lexapro (escitalopram), Luvox (fluvoxamine), Paxil (paroxetine), Prozac (fluoxetine), Zoloft (sertraline)

    dopamine re-uptake inhibitors (DRI) - Cocaine, Provigil (modafinil) 

    norepinephrine re-uptake inhibitors (NRI) - Allegra (nortryptyline), Bontril (phendimetrazine), Duromine (phentermine), Tenuate (diethylpropion)

 

Many Re-Uptake inhibitors affect more than one neurotransmitter ie 

    Adderall (amphetamine) - dopamine & norepinephrine

    Allegron (nortryptyline - serotonin & norepinephrine

    Cymbalta (duloxetine) - serotonin & norepinephrine

    Effexor (venlafaxine) - serotonin & norepinephrine

    Endep (amitriptyline) - serotonin & norepinephrine

    Joncia (milnacipan) - serotonin & norepinephrine

    Pristiq (desvenlafaxine) - serotonin & norepinephrine

    Ritalin (methylphenidate) - dopamine & norepinephrine

​    Vyvanse (lisdexamphetamine) - dopamine & norepinephrine

    Wellbutrin, Zyban (bupropion) - dopamine & norepinephrine

The mechanism of action and the resulting effects of these medications can be reviewed with this video.